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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Neurobiol Dis. 2010 Jun 8;40(1):277–283. doi: 10.1016/j.nbd.2010.05.034

Fig. 2. Niaspan Treatment Of Stroke Reduces Apoptosis, Attenuates TNF-Alpha Expression And Increases VEGF And PI3K Activity.

Fig. 2

Panel A Shows Quantification Field Of View In The Ischemic Border Zone. Panels B–D Show That Niaspan 40mg/Kg Treatment Significantly Decreased The Number Of TUNEL-Positive (B), Cleaved Caspase-3 (C), And TNF-Alpha (D) Expression In The Ischemic Brain Compared To Mcao Control Rats (P<0.05). Panels E–F Show That Niaspan 40mg/Kg Treatment Significantly Increased The Expression Of VEGF (E) And P-PI3K (F) In The Ischemic Border Compared With Non-Treatment Mcao Control Rats (P<0.05). SE = Standard Error. *P< 0.05 Vs Mcao (N=8/Group).