Table 1. Increased scyllo-inositol in frontal cortex and hippocampus in triple transgene mice using HRMAS.

Chemical/Cr	Frontal Cortex		Hippocampus
	Scyllo (n=5)	Reg (n=3)	Scyllo (n=7)	Reg (n=7)
GABA	0.306±.041	0.362±.138	0.356±.157	0.315±.053
Acetate	0.033±.009	0.039±.006	0.049±.017	0.053±.022
Alanine	0.075±.008	0.084±.007	0.060±.019	0.066±.013
Aspartate	0.350±.037	0.317±.080	0.366±.082	0.334±.042
Choline	0.286±.034	0.258±.043	0.171±.049	0.196±.076
Glutamate	1.132±.135	1.106±.099	0.667±.114	0.679±.063
Glutamine	0.360±.060	0.394±.053	0.458±.107	0.368±.031
Glycine	0.116±.017	0.112±.004	0.131±.023	0.134±.025
Lactate	0.806±.081	0.689±.055	0.961±.183	0.819±.228
NAA	0.825±.069	0.796±.075	0.534±.067	0.485±.078
Scyllo-Inositol	0.035±.008*	0.016±.003	0.074±.018*	0.031±.011
Taurine	1.580±.215	1.553±.277	1.07±.230	0.986±.133
myo-Inositol	0.736±.112	0.759±.170	0.701±.110	0.748±.114

Concentrations reported as molar ratios to creatine.

Errors reported are standard deviations.

^*p<0.001; t-test corrected for multiple comparisons