Figure 4.

Organization of the transmembrane Gla protein genes. The positions of intron/exon boundaries are indicated by wedges (▿). Numbers indicate the length (in bp) of intervening introns. The lengths of the introns in the PRGP1 gene (GenBank no. AL356858) are approximate because unresolved gaps of indeterminate length are present in the genomic sequence. Structural features are as follows: SP, signal peptide; PP, propeptide; Gla, Gla domain; TM, transmembrane region; Cyt, cytoplasmic domain; PY, PPXY motif. Chromosome assignments are in parentheses.