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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Neurobiol Dis. 2010 May 26;40(1):193–199. doi: 10.1016/j.nbd.2010.05.024

Figure 2.

Figure 2

Hyperactivation of mTOR in rat brains with chronic spontaneous recurrent seizure. Brains tissues were harvested from rats with chronic spontaneous seizures and aged-matched controls. Rats were treated with rapamycin for 2 days. Phosphorylated S6 and total S6 in rat cortex and hippocampus were visualized by western blots (A) and quantified from three experiments (B) (control: 1.0 ± 0.17; seizure: 1.51 ± 0.12; control treated with rapamycin: 0.16 ± 0.04; seizure treated with rapamycin: 0.13 ± 0.04 in cortex; control: 1.0 ± 0.21; seizure: 1.97 ± 0.43; control treated with rapamycin: 0.16 ± 0.03; seizure treated with rapamycin: 0.20 ± 0.06 in hippocampus)(*P < 0.05, t-test).