Skip to main content
. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Neurobiol Dis. 2010 May 26;40(1):193–199. doi: 10.1016/j.nbd.2010.05.024

Figure 3.

Figure 3

Rapamycin reduces spontaneous recurrent seizures. Rats with spontaneous recurrent seizures were treated with rapamycin (black bar) or vehicle (open bar) for three weeks. Seizure activity was quantified according to average number of seizures (A) (pilocarpine: 39.5 ± 22.96; pilocarpine plus rapamycin: 2.6 ± 0.68) (*P < 0.05, Wilcoxon signed rank test)(A), average total seizure duration (B) (pilocarpine: 1031.9 ± 493.8; pilocarpine plus rapamycin: 69.8 ± 18.37) (*P < 0.05, Wilcoxon signed rank test), and the percentage of rats with at least one seizure (C) (pilocarpine: 100%; pilocarpine plus rapamycin: 60%). (n= 10 per group).