Table 2.
Regimen-related toxicities
| Toxicity | Gradeab |
|||
|---|---|---|---|---|
| Mild–moderate | Severe | Life-threatening | Fatalc | |
| Mucositis | 4 | 49 | 4 | — |
| Dermatitis | 11 | 9 | — | — |
| Enteritis | 34 | 10 | 1 | — |
| VODd | 11 | 35 | 4 | 1 |
| Pulmonary | 9 | 9 | 1 | 2 |
| Cardiac | 2 | 1 | — | — |
| Renal | 13 | 3 | 1 | 1 |
| Cystitis | 21 | 13 | 2 | — |
| Neurologic | — | 4 | 1 | — |
a
Grading was carried out using NCI-Common Toxicity Criteria, v2.0:27 1 = mild, 2 = moderate, 3 = severe, 4 = life-threatening, 5 = fatal.
b
Refers to number of events in 58 patients.
c
Two patients died from toxicity, one with multiorgan involvement.
d
VOD = veno-occlusive disease of the liver.