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Effect of high doses of lidocaine (L3x-4: 3 × 10-4, L-3: 10-3, L3x-3: 3 × 10-3 M) on the reactive oxygen species (ROS) attack. Data are presented as mean ± SE. ACh: acetylcholine, EL(-): before electrolysis. *P < 0.05, compared with ACh 10-7 to 10-6 M of EL(-), †P < 0.05, compared with ACh 10-7 to 10-6 M of the lidocaine 10-5 M (L-5) group.
