Table 3.
Biological processes associated with up-regulated proteins*
| Preconditioned | Injured | Tolerant | |
|---|---|---|---|
| Up-regulated | |||
| 1 | organelle organization | glycolysis | glycolysis |
| 2 | cellular macromolecular complex assembly | glucose catabolic process | glucose catabolic process |
| 3 | cellular component organization | hexose catabolic process | hexose catabolic process |
| 4 | cellular macromolecular complex subunit organization | monosaccharide catabolic process | monosaccharide catabolic process |
| 5 | cellular component assembly | cellular carbohydrate catabolic process | cellular carbohydrate catabolic process |
| 6 | cellular component biogenesis | alcohol catabolic process | alcohol catabolic process |
| 7 | anatomical structure formation | carbohydrate catabolic process | carbohydrate catabolic process |
| 8 | macromolecular complex assembly | glucose metabolic process | glucose metabolic process |
| 9 | macromolecular complex subunit organization | generation of precursor metabolites and energy | hexose metabolic process |
| 10 | nucleosome assembly | hexose metabolic process | monosaccharide metabolic process |
| Up-regulated only under specific conditions | |||
| 1 | muscle thin filament assembly | gluconeogenesis | anti-apoptosis |
| 2 | skeletal myofibril assembly | hexose biosynthetic process | respiratory burst during acute inflammatory response |
| 3 | cardiac myofibril assembly | response to misfolded protein | regulation of protein folding in endoplasmic reticulum |
| 4 | protein polymerization | monosaccharide biosynthetic process | production of molecular mediator of acute inflammatory response |
| 5 | cardiac cell development | glycolysis | negative regulation of apoptosis |
| 6 | cardiac muscle cell development | pyruvate metabolic process | negative regulation of programmed cell death |
| 7 | cytoskeleton organization | acute inflammatory response | negative regulation of cell death |
| 8 | cellular component assembly | alcohol biosynthetic process | oxygen transport |
| 9 | microtubule-based process | glucose catabolic process | regulation of apoptosis |
| 10 | cellular component organization | hexose catabolic process | gas transport |
*
All listed processes were significantly regulated with p values ≤ 0.01, as a result of bioinformatic analyses of up-regulated proteins with the MetaCore program. Please see Table S2 for down-regulated biological processes.