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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Ann Neurol. 2010 Feb;67(2):250–257. doi: 10.1002/ana.21896

FIGURE 4.

FIGURE 4

Increase in response latency due to interictal spike (IIS). The length of time between the presentation of the match lever and pressing of that lever by the rat was quantified as response latency. The figure shows histograms of the relative frequencies of response latency in trials without IIS (thick solid line) and trials with IIS (thick dashed line). The median response latency to press the match lever was 2.28 seconds in trials without IIS (thin solid line), whereas if an IIS occurred the median increased to 2.76 seconds (thin dashed line; p < 0.001; n = 4,609 trials adjusted for five individual rats).