Fig. 5.

Notch mutant clones show a wild-type differentiation pattern. (A-D) A single mCD8-GFP labelled Notch loss-of-function clone that contains Dpn (red) positive neuroblasts aberrantly positioned in the medulla cortex. Newly born progeny close to the neuroblasts do not express the neuronal marker Elav (arrows), whereas more mature progeny that are positioned further away from the neuroblast upregulate Elav. This differentiation pattern is similar to that observed for wild-type neuroblasts at the medial edge (yellow arrowheads). Scale bar: 10 μm.