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. 2010 Sep 15;137(18):3079–3088. doi: 10.1242/dev.048744

Fig. 3.

Fig. 3.

An FpnKI allele fails to complement the Fpn1ffe mutation. (A-H) Lateral view of wild-type (A,C,E), Fpn1ffe/ffe (B) and Fpn1ffe/KI mutant (D,F-H) embryos at E10.5 (A-D,G,H) and E9.5 (E,F). Fpn1ffe/KI mutants are developmentally delayed and exhibit severe NTDs that consists of exencephaly (between arrowheads in B), spina bifida and craniorachischisis. (A-F) Lateral views with anterior towards the left. (G) Dorsal view. (H) Frontal view.