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. Author manuscript; available in PMC: 2011 Jul 19.
Published in final edited form as: Vaccine. 2010 Jun 4;28(32):5280–5287. doi: 10.1016/j.vaccine.2010.05.054

Figure 5.

Figure 5

Epitope binding to Aβ42 peptide by the immune sera of BALB/cJ mice vaccinated with Aβ42 gene vaccine measured by ELISA showing that immune sera (1:400) mainly binds to Aβ1-42, Ab1-28 and Aβ9-18. The immune sera also show binding to Aβ1-9 and Aβ16-38 with a low titer. Shown are means and SD of 4 mice in each group after 7 vaccinations and the experiment was repeated three times. Black bars show Aβ peptides bound by antibodies in sera from Gal4/UAS-Aβ42 trimer immunized mice, hatched bars show antibody binding by antibodies from sera of Gal4/UAS-Aβ42 monomer immunized mice. Grey bars show antibody binding by antisera derived from CMV-Aβ42 trimer immunization. White bars show the reactivity of control serum. * P < 0.05 compared with control.