Table 3.
Detoxifying proteins induced by lycopene in LNCaP and androgen-depleted LNCaP cells. Protein name, gene name, human International Protein Index (ipi) database number, ProteinProphet™ probability, location where protein was identified, and normalized expression ratio of lycopene treated over placebo control are listed.
| LNCaP | |||||
|---|---|---|---|---|---|
| Protein | Gene | ipi | Probability | Sub-cellular Location |
Express ratio mean (lyc/pb)* |
| Epoxide hydrolase 1 | EPHX1 | IPI00009896 | 1 | nucleus | 1.08 ± 0.06 |
| Superoxide dismutase 1 | SOD1 | IPI00218733 | 1 | nucleus | 1.53 ± 0.00 |
| Serotransferrin precursor | TF_ | IPI00022463 | 0.93 | nucleus | 1.14 ± 0.00 |
| Superoxide dismutase 1 | SOD1 | IPI00218733 | 1 | cytosol | 1.06 ± 0.10 |
| Androgen-depleted LNCaP | |||||
|---|---|---|---|---|---|
| Protein | Gene | ipi | Probability | Sub-cellular Location |
Express ratio mean (lyc/pb)* |
| Epoxide hydrolase 1 | EPHX1 | IPI00009896 | 0.98 | nucleus | 4.46 ± 0.00 |
| Catalase | CAT | IPI00465436 | 1 | cytosol | 6.41 ± 0.78 |
| Superoxide dismutase 1 | SOD1 | IPI00218733 | 1 | cytosol | 1.08 ± 0.17 |
*
Protein probability>0.5 and pvalue<e−01 are reported.