FIG. 2.

Maximum-likelihood phylogenetic tree of HIV-2 RT sequences from PBMCs, CVL-RNA, and CVL-DNA from four ARV-naive females. Potential ARV resistance mutations (M184I, A62V) found in CVL of two subjects are shown. Inset: Example of Slatkin–Maddison test for compartmentalization of CVL versus PBMC sequences for subject MIN1974. The tree shows traced character states corresponding to CVL (black lines) and PBMCs (white lines). There are two steps required to move along the tree between CVL and PBMCs. The histogram shows the of number of steps found during 1000 random character (taxa) shuffles on the ML tree.