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The K1 values for ATP and ADP inhibition and the Km values for CoQ10 activation of H+ transport in proteoliposomes reconstituted with E. coli expressed UCP1, UCP2, and UCP3 at pH 6.8 and 10°C
| IB-UCP |
Ki
(μM)
|
KiATP/KiADP | Km (nmol) | |
|---|---|---|---|---|
| ATP | ADP | |||
| UCP1* | 0.05 | 0.08 | 0.62 | 0.3 |
| UCP2 | 0.09 | 0.19 | 0.47 | 1.14 |
| UCP3 | 0.23 | 0.08 | 2.87 | 1.13 |
Values from ref. 42. UCP1 is from hamster, UCP2 and -3 from human.
