Table 1.

Nuclear Smad3 and N-Cadherin Expression in Benign Cystadenoma, Borderline Tumor, and Cystadenocarcinoma Tissue Microarrays

	Frequency of Average Scores			P	Total No. Patients
	0	<1.5	≥1.5
Smad3				0.031*
Benign	0	4	16	1.0 (benign versus borderline)	20
Borderline	0	6	24	0.0099 (borderline versus carcinoma)	30
Cystadenocarcinoma	0	20	19	0.0257 (benign versus carcinoma)	39
N-Cadherin				0.996*
Benign	2	12	5	0.0669 (benign versus borderline)	19
Borderline	5	24	1	0.773 (borderline versus carcinoma)	30
Cystadenocarcinoma	14	22	4	0.0319 (benign versus carcinoma)	40

NOTE: Pairwise contrast (logistic regression) between tissue categories are comparing (a) Smad3 average scores of <1.5 versus average scores of ≥1.5 and (b) N-cadherin average scores of 0 versus average scores of ≥1.5.

^*Cox proportional hazards regression analysis using Smad3 or N-cadherin as a continuous variable.