Figure 3. TH1- or TH17-polarization is required for enhanced IIC response and viral control.
Naïve, TH1-, TH17-, TH2-polarized or TH0 unpolarized memory HNT cells were transferred to BALB/c hosts then infected with A/PR8. (a) Levels of IIC in lungs 40 hrs post-infection (n = 5). (b) Pulmonary viral titers (n = 5 per day). Error bars indicate SD; * P < 0.05, ** P < 0.005, *** P < 0.001 (one-way ANOVA followed by Bonferroni’s post hoc test).