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. 2010 Aug 3;4:44. doi: 10.3389/fnbeh.2010.00044

Figure 3.

Figure 3

Extracellular-related kinase phosphorylation in the amygdala and mPFC following extinction training. (A) Schematic showing the behavioral procedures in this experiment. (B) Freezing during the CS for animals (N = 16) given extinction training and testing. (C) Freezing during the extinction training session for rats included in the western blot analysis. Expression of phosphorylated ERK in the amygdala (D) and mPFC (E) in rats given no extinction (N = 8, green), 4 trials of extinction (N = 7, blue) or 40 trials of extinction (N = 9, orange) compared to home cage rats (N = 8, gray). Levels of total ERK in the amygdala (F) and mPFC (G) in the same set of rats. The graphs show mean optical density (OD) values (±SEM) for each treatment group (*p < 0.05 relative to HC; **p < 0.01 relative to HC; ^p < 0.05 relative to 4 EXT).