Table 3.

Association of candidate gene DNA markers with weight of the adrenal gland in the PiF1a line

Gene	Genotype		Genotype		Genotype
Trait*	LSM1,2	SE2	LSM	SE	LSM	SE	p-value
	(n)		(n)		(n)		q-value3
RYR1 c.1843C>T	CC		CT		TT
Adrenal Weight (g)	2.29	0.03	2.22	0.03	na4		0.073
	(98)		(107)				0.31
POMC c.293_298del	InsIns		InsDel		DelDel
Adrenal Weight (g)	2.24	0.02	2.40	0.07	na		0.027
	(179)		(22)				0.19
MC2R c.306T>G	TT		TG		GG
Adrenal Weight (g)	2.11	0.04	2.31	0.03	na		<0.0001
	(59)		(142)				<0.0001
NR3C1 c.*2122A>G	AA		AG		GG
Adrenal Weight (g)	2.11a	0.05	2.29b	0.03	2.30b	0.05	0.003
	(42)		(119)		(45)		0.04
UCN g.1329T>C	TT		TC		CC
Adrenal Weight (g)	2.21	0.03	2.33	0.04	na		0.019
	(146)		(54)				0.17
CRHR2 c.*13T>C	TT		TC		CC
Adrenal Weight (g)	2.31e	0.04	2.24	0.03	2.18f	0.05	0.087
	(77)		(91)		(38)		0.33

¹LSM: least square mean; SE: standard error

²LSM with different superscripts ^{a,b; c,d; e,f} differ at p < 0.01; p < 0.05; and p < 0.1 respectively

³q-value: false discovery rate

⁴na: not available or not analyzed due to low frequency n < 10;