Fig. 1.
Change in transepithelial resistance from baseline (ΔRT) in response to simulated reflux and control challenges. (A) Acidic pepsin. (B) Acid-only. (C) Pepsin-only. Reversibility assessment of reductions in RT following acidic pepsin and acid-only challenges is also represented (30_Rinse) in (A) and (B). Negative ΔRT values suggest a decrease in resistance from baseline, whereas positive ΔRT suggest an increase from baseline. ΔRT for control challenges and pepsin-only challenge (C) remained positive, while ΔRT for acidic pepsin (A) and acid-only (B) challenges decreased. Error bars represent standard errors.