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Light microphotographs of representative vocal fold samples obtained after 30 minutes of challenge exposure (hematoxylin and eosin stain, 40× magnification). (A) Control. (B) Acidic pepsin (pH 3). (C) Acid-only (pH 3). (D) Pepsin-only (pH 7). Ep = stratified squamous epithelium; LP = lamina propria; arrowhead = epithelial shedding; dashed oval = sub-basilar edema or vacuolization; * = interstitial edema.
