Table 1.
The percentage of P. aeruginosa isolates that were non-susceptible to antimicrobials and demonstrated overexpression of efflux genes and ampC β-lactamase, coupled with oprD down-regulation.
| Antimicrobial | Non-susceptible (n = 59) | % of isolates (n) | |||
|---|---|---|---|---|---|
| ABM+ (16) | XY+ (30) | AmpC+ (07) | OprD- (41) | ||
| Aztreonam | 21 (35.6) | 56.3 (09) | 43.3 (13) | 71.4 (05) | 34.1 (14) |
| Imipenem | 31 (52.5) | 56.3 (09) | 80.0 (24) | 71.4 (05) | 65.9 (27) |
| Meropenem | 31 (52.5) | 62.5 (10) | 80.0 (24) | 71.4 (05) | 63.4 (26) |
| Cefepime | 30 (50.8) | 56.3 (09) | 80.0 (24) | 85.7 (06) | 58.5 (24) |
| Ceftazidime | 33 (55.9) | 50.0 (08) | 76.7 (23) | 100 (07) | 63.4 (26) |
| Amikacin | 35 (59.3) | 68.8 (11) | 86.7 (26) | 57.1 (04) | 70.7 (29) |
| Gentamicin | 40 (67.8) | 75.0 (12) | 86.7 (26) | 57.1 (04) | 65.9 (27) |
| Ciprofloxacin | 38 (64.4) | 81.3 (13) | 86.7 (26) | 85.7 (06) | 63.4 (26) |
The abbreviations ABM+, XY+ and AmpC+ designate MexAB-OprM, MexXY, and AmpC overexpression, respectively.
OprD -: OprD porin down-regulation.