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. 2010 Aug 10;11:121. doi: 10.1186/1471-2350-11-121

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Copyright ©2010 Huang et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Pedigree structure and haplotype analysis at the RP25 locus. Blackened bars indicate the disease haplotype. Filled squares or filled circles represent male or female individuals affected with RP, respectively. Arrow points to the proband (II2). All patients in the arRP family carry the homozygous haplotype between single nucleotide polymorphisms rs4710292 and rs4710437. The genomic positions of two markers are from Human (Homo sapiens) Genome Browser Gateway, the GRCh37 build version, and six SNPs are from NCBI B37.1 assembly.