Table 3. Comparison of responses in M. Africanum versus M. Tuberculosis infected TB cases.
Stimulation | Group | n = | IFN-γ | TNF-α | IL-10 | IL-12(p40) | IL-13 | IL-17 | IL-18 |
PPD | TB CASE | 21 | 2832[822–5679] | 346[83–602] | 97[24–236] | 265[14–488] | 35[10–45] | 118[28–172] | 2[0–9] |
MA CASE | 14 | 2495[1120–6082] | 529[126–750] | 152[62–301] | 152[0–499] | 28[13–49] | 116[76–222] | 0[0–6] | |
EC | TB CASE | 21 | 440[130–1472] | 44[0–122] | 7[0–58] | 0[0–103] | 6[0–19] | 57[0–82] | 0[0–0.9] |
MA CASE | 14 | 360[0–590] | 115[0–137] | 0[0–13] | 74[0–373] | 1.2[0–11] | 0[0–48] | 0[0–0.5] | |
TB10.4 | TB CASE | 21 | 338[120–496] | 455[154–937] | 73[0–237] | 613[107–943] | 0[0–5] | 0[0–42] | 1[0–9] |
MA CASE | 14 | 252[0–1930] | 744[414–1924] | 163[22–406] | 939[80–2666] | 0[0–10] | 0[0–80] | 0.7[0–6] |
TB = M. tuberculosis, MA = M. africanum. 0 = below limit of detection for assay; after background subtraction, negative values were converted to 0.