Table 6.

 Risk of mortality from stroke* according to migraine status in men and women in Reykjavik Study (n=18 725†). Figures are age and multivariable‡ adjusted hazard ratios (95% confidence intervals)

	No headache	Non-migraine headache§	Migraine	Migraine without aura¶	Migraine with aura**
Men
Died/total	373/7068	63/1405	37/571	6/128	31/443
Age adjusted	1.00	0.92 (0.70 to 1.20)	1.46 (1.04 to 2.05)††	0.97 (0.43 to 2.18)	1.62 (1.12 to 2.34)††
Multivariable adjusted	1.00	0.90 (0.69 to 1.18)	1.55 (1.10 to 2.18)††	0.96 (0.43 to 2.15)	1.76 (1.22 to 2.54)††
Women
Died/total	292/6003	99/2226	63/1452	18/498	45/954
Age adjusted	1.00	1.08 (0.86 to 1.36)	1.20 (0.91 to 1.58)	1.05 (0.65 to 1.69)	1.27 (0.92 to 1.74)
Multivariable adjusted	1.00	1.08 (0.86 to 1.36)	1.20 (0.91 to 1.59)	1.08 (0.67 to 1.75)	1.26 (0.92 to 1.73)
Men and women
Died/total	665/13 071	162/3631	100/2023	24/626	76/1397
Age-sex adjusted	1.00	1.01 (0.85 to 1.20)	1.27 (1.03 to 1.58)††	1.01 (0.67 to 1.53)	1.38 (1.09 to 1.76)††
Multivariable adjusted	1.00	1.00 (0.84 to 1.19)	1.30 (1.05 to 1.61)††	1.06 (0.70 to 1.60)	1.40 (1.10 to 1.78)††

*ICD-9 codes 431, 433, 434, 436, 438 and ICD-10 codes I61, I63, I64, I66, and I69.

†Of original 18 903 participants, 68 (0.36%) were lost to follow-up and 110 (0.58%) had missing data on blood pressure, cholesterol concentration, or BMI, leaving n=18 725 with 470 990 years of follow-up.

‡Age, BMI, smoking (no, current, previous), education (primary, secondary, college/university), systolic and diastolic blood pressure, and use of antihypertensive drugs.

§Headache without or with one symptom of migraine once or more a month.

¶2-3 of unilateral, photophobia, nausea symptoms.

**Migraine with visual or sensory symptoms, or both. Participants with symptoms of migraine without aura and migraine with aura were classified as migraine with aura.

††Significant at P<0.05.