Table 2.

Risk of incident AF according to birth weight categories

	Birth weight category, in kg
	<2.5 (n=2962)	2.5 – 3.2 (n=7228)	3.2 – 3.9 (n=14214)	3.9 – 4.5 (n=2785)	≥4.5 (n=793)	p_{linear trend}
Number of events	59	172	369	100	35	-
Age-adjusted incidence rate	1.45	1.82	1.88	2.57	2.55	-
Age-adjusted relative risk	Referent	1.27 (0.95–1.71)	1.31 (1.00–1.72)	1.75 (1.27–2.41)	1.76 (1.16–2.67)	0.0004
Multivariable model 1^*	Referent	1.30 (0.96–1.75)	1.28 (0.96–1.69)	1.70 (1.23–2.37)	1.71 (1.12–2.61)	0.002
Multivariable model 2^†	Referent	1.31 (0.97–1.77)	1.27 (0.96–1.68)	1.68 (1.21–2.34)	1.63 (1.07–2.50)	0.004
Multivariable model 3^‡	Referent	1.28 (0.94–1.73)	1.13 (0.85–1.50)	1.43 (1.02–1.99)	1.34 (0.87–2.05)	0.17
Multivariable model 4^§	Referent	1.27 (0.94–1.71)	1.10 (0.83–1.46)	1.41 (1.01–1.96)	1.29 (0.84–1.98)	0.23

Data are counts, rates per 1000 person-years of follow-up or hazard ratios (95% confidence intervals)

Adjusted for age, hypercholesterolemia, smoking, exercise, alcohol consumption, education, race/ethnicity and hormone replacement therapy. Due to missing covariates, the multivariable model was based on 715 events in 27174 women.

^†

Additionally adjusted for body mass index, systolic blood pressure, diastolic blood pressure and diabetes. Due to missing covariates, the multivariable model was based on 696 events in 26368 women.

^‡

Additionally adjusted for adult height. Due to missing covariates, the multivariable model was based on 696 events in 26368 women.

^§

Additionally adjusted for maximum body weight between ages 18 and 30 years. Due to missing covariates, the multivariable model was based on 689 events in 25992 women.