Table 2.
Genotype and allele distribution of ADD1 (Gly460Trp) gene polymorphism among hypertensive cases and controls.
| Gly460Trp | Cases (n =432) | Controls (n=461) | OR (95% CI) | P value | ORa (95% CI) | P value |
|---|---|---|---|---|---|---|
| Genotype | ||||||
| Gly/Gly | 255 (59.1) | 293 (63.6) | 1.0 | Ref | 1.0 | Ref |
| Gly/Trp | 154 (35.6) | 149 (32.3) | 1.2 (0.9 -1.6) | 0.2 | 1.1 (0.8 -1.6) | 0.3 |
| Trp/Trp | 23 (5.3) | 19 (4.1) | 1.4 (0.7 - 2.6) | 0.3 | 1.3 (0.8 - 3.0) | 0.3 |
| Allele | ||||||
| Gly | 0.77 | 0.80 | 1.2 (0.9-1.5) | 0.2 | ||
| Trp | 0.23 | 0.20 |
Values in parenthesis indicate percentage
a
Odds ratio according to genotype was estimated after adjusting the cofounding variables for age, smoking and alcohol consumption