Table 3.
Inverse correlation between stromal Cav-1 and epithelial p-Akt during tumor progression
| Stromal Cav-1 Status | p-Akt Status | |||
|---|---|---|---|---|
| Absent (0) | Present (1+2) | Absent (0) | Present (1) | |
| N = 53 | N = 44 | N = 58 | N = 43 | |
| Tumor Progression | ||||
| Benign | 4% (2) | 64% (28) | 45% (26) | 9% (4) |
| PCa | 32% (17) | 36% (16) | 26% (15) | 46% (20) |
| Mets | 64% (34) | 0% (0) | 29% (17) | 45% (19) |
Test used: Fisher’s exact test
Stromal Cav-1 status, absent versus present; p-value = 4.21 × 10−16
p-Akt status, absent versus present; p-value = 3.63 × 10−4
Stromal Cav-1 versus p-Akt; p-value = 2.66 × 10−10