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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Pediatr Crit Care Med. 2010 May;11(3):349–355. doi: 10.1097/PCC.0b013e3181c519b4

Table 3.

A: Top signaling and metabolic pathways represented by the 1,762 upregulated genes based on neutrophil-derived RNA
PATHWAY P VALUE # OF GENES
Protein ubiquitination pathway 6.8E-6 32
NRF2-mediated oxidative stress response 5.5E-5 27
Mitochondrial dysfunction 7.1E-5 22
Oxidative phosphorylation 1.4E-4 22
PI3K/Akt signaling 4.8E-3 16
B: Top signaling and metabolic pathways represented by the 804 upregulated genes based on monocyte-derived RNA.
PATHWAY P VALUE # OF GENES
Calveolar-mediated endocytosis 9.6E-7 13
NRF2-mediated oxidative stress response 4.0E-5 18
IL-10 signaling 2.5E-4 9
Leukocyte extravasation signaling 3.3E-3 14
IL-12 signaling in macrophages 4.3E-3 10