Table 4.
A: Top signaling and metabolic pathways represented in the 643 downregulated genes from neutrophil-derived RNA. | ||
---|---|---|
PATHWAY | P VALUE | # OF GENES |
Antigen presentation pathway | 3.1E-9 | 10 |
Interferon signaling | 5.4E-5 | 6 |
Hepatocyte growth factor signaling | 2.5E-4 | 9 |
Pattern recognition receptor signaling | 5.5E-4 | 8 |
Eicosanoid signaling | 5.6E-4 | 7 |
B: Top signaling and metabolic pathways represented in the 161 downregulated genes from monocyte-derived RNA. | ||
---|---|---|
PATHWAY | P VALUE | # OF GENES |
Antigen presentation pathway | 4.2E-9 | 6 |
Dendritic cell maturation | 2.9E-5 | 6 |
IL-4 signaling | 1.5E-4 | 4 |
CTLA4 signaling in cytotoxic T lymphocytes | 3.6E-4 | 4 |
Allograft rejection signaling | 4.2E-4 | 3 |
C: Top signaling and metabolic pathways represented in the 77 downregulated genes from lymphocyte-derived RNA. | ||
---|---|---|
PATHWAY | P VALUE | # OF GENES |
NK cell signaling | 3.7E-7 | 6 |
iCOS signaling in T helper cells | 8.0E-6 | 6 |
CD28 signaling in T helper cells | 1.3E-5 | 6 |
Calcium-induced T lymphocyte apoptosis | 1.7E-5 | 5 |
CTLA4 signaling in cytotoxic T lymphocytes | 8.0E-5 | 5 |