Table 1. Genetic regions showing multipoint NPL LOD ≥ 2.0.

	Location			Study allele frequency		CEPH allele frequency
Marker	cM	cyto	Mbp	LOD	p-value	LOD	p-value
D3S240	219.97	3q29	195.6	0.58	0.05	2.61	0.0003
D4S2999*	152.70	4q31.3	155.0	0.69	0.04	2.13	0.0009
D7S2459	120.05	7q22.3	107.1	1.44	0.005	2.02	0.0012
D7S525*	121.35	7q31.1	109.4	1.76	0.002	2.78	0.0002
D7S2418	122.15	7q31.1	109.8	1.63	0.003	2.49	0.0004
D7S471*	122.82	7q31.1	111.8	1.51	0.004	2.37	0.0005
D7S486	124.82	7q31.2	115.7	1.46	0.005	2.14	0.0009
D7S633*	125.99	7q31.2	116.8	1.82	0.002	2.97	0.00011
D7S643*	126.81	7q31.31	120.5	2.01	0.0012	3.08	0.00008
D7S685*	127.87	7q31.32	121.1	2.00	0.0012	2.95	0.00011
D7S2529*	128.64	7q31.32	122.2	1.89	0.002	2.75	0.0002
D7S2520*	129.44	7q31.32	123.4	1.90	0.002	2.51	0.0003
D7S648	129.45	7q31.33	123.6	1.90	0.002	2.50	0.0003
D7S2203*	130.56	7q31.33	125.1	1.99	0.0012	2.99	0.0001
D7S1873*	131.07	7q31.33	125.9	1.99	0.0012	2.77	0.0002
D7S680*	131.23	7q31.33	126.5	1.91	0.002	2.57	0.0003
D7S514	131.55	7q31.33	126.8	1.73	0.002	2.36	0.0005
D7S530	133.20	7q32.1	129.0	1.44	0.005	2.12	0.0009
D7S2519*	133.67	7q32.2	129.8	1.42	0.005	2.20	0.0007

^*indicates markers used for fine mapping. The location (cM) is derived from published deCODE data and used for linkage analysis in this study ²⁶. The cytogenetic and physical location is from UCSC Genome Browser March 2006 assembly. Bonferroni-corrected p-value for multiple comparisons for the full genome scan at D7S643 is 0.086 (0.00008*1081 markers).