TABLE 1.
Incidence rates of type 1 diabetes among Italian children 0–14 years old in the years 1990–2003 by sex, age-group, calendar period, and geographical area of residence
Incident cases (n) | Person-years at risk (n) | Incidence rates per 100,000 person-years (95% CI) | % Estimated completeness of ascertainment (range) | |
---|---|---|---|---|
All | 5,180 | 42,246,144 | 12.26 (11.93–12.60) | |
Boys | 2,840 | 21,629,264 | 13.13 (12.66–13.62) | |
Girls | 2,340 | 20,616,878 | 11.35 (10.90–11.82) | |
Age-group (years) | ||||
0–2 | 479 | 7,984,265 | 6.00 (5.49–6.56) | |
3–5 | 961 | 8,002,496 | 12.01 (11.27–12.79) | |
6–8 | 1,118 | 8,259,614 | 13.54 (12.77–14.35) | |
9–11 | 1,366 | 8,672,116 | 15.75 (14.94–16.61) | |
12–14 | 1,256 | 9,327,652 | 13.47 (12.74–14.23) | |
Calendar period | ||||
1990–1992 | 1,089 | 10,659,853 | 10.22 (9.63–10.84) | |
1993–1995 | 1,139 | 9,871,152 | 11.54 (10.89–12.23) | |
1996–1998 | 1,184 | 9,297,165 | 12.74 (12.03–13.48) | |
1999–2001 | 1,091 | 7,836,490 | 13.92 (13.12–14.77) | |
2002–2003 | 677 | 4,581,483 | 14.78 (13.7–15.93) | |
Birth cohort | ||||
1975–1981 | 273 | 2,536,714 | 10.76 (9.56–12.12) | |
1978–1984 | 560 | 4,440,171 | 12.61 (11.61–13.70) | |
1981–1987 | 819 | 6,100,235 | 13.43 (12.54–14.38) | |
1984–1990 | 1,012 | 7,278,051 | 13.90 (13.07–14.79) | |
1987–1993 | 1,047 | 8,137,636 | 12.87 (12.11–13.67) | |
1990–1996 | 715 | 6,285,553 | 11.38 (10.57–12.24) | |
1993–1999 | 457 | 4,186,785 | 10.92 (9.96–11.96) | |
1996–2002 | 226 | 2,385,021 | 9.48 (8.32–10.80) | |
1999–2003 | 71 | 895,977 | 7.92 (6.28–10.00) | |
Northern Italy | 945 | 8,006,808 | 11.80 (11.07–12.58) | |
Turin | 419 | 3,823,910 | 10.96 (9.96–12.06) | 99.0 (98.2–99.4) |
Liguria | 280 | 2,377,687 | 11.78 (10.47–13.24) | 98.2 (96.7–99.0) |
Pavia | 93 | 768,584 | 12.10 (9.87–14.83) | 99.0 (97.8–99.8) |
Modena | 74 | 613,452 | 12.06 (9.61–15.15) | 99.3 (98.1–100) |
Trento | 79 | 423,175 | 18.67 (14.97–23.27) | 99.4 (98.7–100) |
Central-Southern Italy | 2,728 | 30,550,760 | 8.93 (8.6–9.27) | |
Firenze-Prato | 214 | 1,923,090 | 11.13 (9.73–12.72) | 98.8 (98.0–100) |
Marche | 284 | 2,696,075 | 10.53 (9.38–11.83) | 99.0 (97.8–99.9) |
Lazio | 678 | 7,522,247 | 9.01 (8.36–9.72) | 97.0 (95.3–98.8) |
Umbria | 145 | 1,255,832 | 11.55 (9.81–13.59) | 99.0 (98.0–100) |
Abruzzo | 115 | 1,196,101 | 9.61 (8.01–11.54) | 98.1 (97.2–100) |
Campania | 1,292 | 15,957,414 | 8.10 (7.67–8.55) | 96.2 (94.2–98.5) |
Island | ||||
Sardinia | 1,507 | 3,688,576 | 40.86 (38.84–42.97) | 91.0 (89.0–96.0) |