Figure 5.
Reduced dark sensitivity and normal light adaptation in Gγ1+/− mice. A, B, Response amplitudes, R, of ERG b-waves (A) and a-waves (B) from WT and Gγ1+/− mice were normalized to the maximal values measured in the dark (Rmax, dark) and plotted as functions of flash strength. Data points were fitted as in Figure 2, A and B. The fits are shown as solid lines, and the corresponding parameters for Gγ1+/− mice are summarized in Table 3. C, D, The rod- and cone-driven components of the b-wave stimulus–response curves in A are plotted individually as in Figure 2C. Color code: Dark-adapted mice, black; light adapted at 0.005 cd/m2, red; 0.1 cd/m2, green; 1 cd/m2, blue.