. Author manuscript; available in PMC: 2010 Aug 25.

Published in final edited form as: Nat Neurosci. 2008 Feb 17;11(3):309–317. doi: 10.1038/nn2055

Table 1. Endocrine characteristics of Type 1 and Type 2 diabetes in rodents with different levels of corticosterone.

Data were analyzed using 2 × 2 ANOVA and asterisk (*) indicates significance at p < 0.05 relative to sham–operated non–diabetic controls. Values shown are means and s.e.m. Abbreviations: STZ = streptozocin; SHAM = sham–operated, ADX + CORT = adrenalectomized with 25 μg ml^–1 corticosterone replacement.

		FASTING GLUCOSE (mg dL^–1)	FED GLUCOSE (mg dL^–1)	INSULIN (ng ml^–1)	CORTICOSTERONE (ng ml^–1)
wildtype	SHAM	71.77 (8.63)	140.65 (15.67)	1.41 (0.15)	46.16 (15.99)
	ADX+CORT	64.80 (1.87)	95.95 (20.65)	1.41 (0.14)	18.85 (3.95)
db/db	SHAM	330.27 (21.01)*	334.12 (41.09)*	3.16 (0.68)*	258.55 (43.11)*
	ADX+CORT	98.40 (17.51)	328.88 (19.83)*	1.03 (0.17)	11.24 (2.21)
Vehicle	SHAM	30.19 (5.77)	129.86 (21.72)	2.07 (0.27)	53.08 (17.72)
	ADX+CORT	44.74 (2.23)	170.87 (11.74)	1.73 (0.27)	19.87 (4.56)
STZ	SHAM	290.96 (35.94)*	318.46 (16.76)*	0.79 (.09)*	418.24 (18.26)*
	ADX+CORT	221.08 (14.80)*	263.06 (11.29)*	0.91 (0.16)*	30.14 (5.78)