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. Author manuscript; available in PMC: 2011 Apr 2.
Published in final edited form as: Circ Res. 2010 Feb 18;106(6):1164–1173. doi: 10.1161/CIRCRESAHA.109.209767

Figure 2. Impaired BK channel function and vasoreactivity of coronary arteries in STZ-induced diabetic rats.

Figure 2

A: Whole-cell K+ currents and BK channel I–V curves from diabetic rats at baseline, after the application of Ang II, IBTX, and washout of chemicals. BK currents in diabetic SMC was significantly reduced with loss of the Ang II effects. Dashed line indicates the I–V curve at baseline of control rats. B: Impaired reactivity of coronary arteries from STZ-induced diabetic rat in response to Ang II, IBTX and NS-1619. *: p<0.05 vs. control.