Table 3.
Patient | Primary cancer | Non-tumor tissue | Tumor tissue | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Fibrosis | Methylight | MSP | IRS | Methylight | MSP | IRS | ||||
score | Result | PMR | Result | PMR | ||||||
Liver metastasis (M) | ||||||||||
M1 | breast | 1 | neg | 0.05 | nd | 3 | neg | 0.02 | nd | 6 |
M2 | breast | 0 | neg | 0.04 | nd | 2 | neg | 0.01 | nd | 6 |
M3 | colorectal | 0 | neg | 0.01 | nd | 0 | neg | 0.01 | nd | 4 |
M4 | colorectal | 0 | neg | 0.01 | nd | 0 | neg | 0.01 | nd | 6 |
M5 | colorectal | 0 | neg | 0.01 | nd | 0 | neg | 0.01 | nd | 3 |
M6 | colorectal | 0 | neg | 0.01 | nd | 0 | neg | 0.01 | nd | 6 |
M7 | colorectal | 4 | neg | 0.01 | nd | 0 | neg | 0.01 | nd | 5 |
M8 | colorectal | 0 | neg | 0.01 | nd | 0 | neg | 0.01 | nd | 5 |
M9 | colorectal | 0 | neg | 0.01 | nd | 0 | neg | 0.01 | nd | 6 |
M10 | colorectal | 0 | neg | 0.01 | nd | 0 | neg | 0.01 | nd | 5 |
M11 | colorectal | 0 | neg | 0.01 | nd | 2 | pos | 39.55 | nd | 4 |
M12 | colorectal | 0 | neg | 0.01 | nd | 0 | neg | 0.01 | nd | 6 |
M13 | colorectal | 0 | neg | 0.01 | neg | 0 | neg | 0.01 | neg | 6 |
M14 | colorectal | 0 | neg | 0.02 | pos | 0 | neg | 0.01 | pos | 6 |
M15 | colorectal | 0 | neg | 0.01 | neg | 0 | pos | 52.18 | neg | 6 |
M16 | colorectal | 0 | neg | 0.09 | neg | 0 | neg | 0.74 | neg | 6 |
M17 | colorectal | 0 | neg | 0.39 | neg | 2 | neg | 0.04 | neg | 6 |
M18 | colorectal | 0 | neg | 0.73 | neg | 0 | neg | 0.12 | neg | 5 |
M19 | colorectal | 0 | neg | 0.15 | neg | 0 | neg | 0.01 | neg | 5 |
M20 | colorectal | 0 | neg | 0.17 | pos | 2 | neg | 0.01 | neg | 4 |
M21 | colorectal | 0 | neg | 0.8 | neg | 3 | pos | 57.82 | pos | 0 |
M22 | colorectal | 0 | neg | 0.54 | pos | 2 | neg | 0.35 | neg | 5 |
M23 | colorectal | 2 | neg | 0.55 | pos | 0 | neg | 0.51 | neg | 6 |
M24 | colorectal | 0 | neg | 0.38 | neg | 0 | pos | 9.88 | pos | 0 |
M25 | colorectal | 0 | neg | 0.08 | pos | 0 | pos | 6.48 | neg | 5 |
M26 | gastric | 0 | neg | 0.01 | pos | nd | neg | 0.01 | neg | nd |
M27 | gastric | 0 | neg | 0.39 | neg | nd | neg | 0.15 | neg | nd |
M28 | colorectal | 0 | neg | 0.09 | neg | nd | pos | 25.19 | neg | nd |
M29 | colorectal | 0 | neg | 0.85 | pos | nd | neg | 0.07 | pos | nd |
M30 | colorectal | 0 | neg | 0.86 | neg | nd | neg | 0.49 | neg | nd |
M31 | colorectal | 0 | neg | 0.55 | pos | nd | neg | 1.19 | pos | nd |
M32 | renal | 0 | neg | 0.01 | nd | nd | neg | 0.01 | nd | nd |
M33 | colorectal | 1 | neg | 0.08 | nd | nd | neg | 0.85 | nd | nd |
M34 | colorectal | 0 | neg | 0.03 | nd | nd | neg | 0.01 | nd | nd |
PMR, percentage of methylated reference (%); MSP, methylation specific PCR; nd, not done;