Table 2.
Selected top enriched GO terms
| ID | Term | F | H | K | L | N | O | P | Q | Lova | Taxol |
|---|---|---|---|---|---|---|---|---|---|---|---|
| GO:0003723 | RNA Binding | 0.0 | 1.2 | 3.0 | 0.3 | 1.9 | 0.4 | 0.1 | 7.2 | 0.2 | 0.0 |
| GO:0006412 | Translation | 0.0 | 1.2 | 4.4 | 1.1 | 5.1 | 0.4 | 0.7 | 5.8 | 1.2 | 0.0 |
| GO:0045765 | Regulation of angiogenesis | 0.0 | 0.0 | 1.1 | 1.1 | 1.1 | 3.7 | 0.2 | 1.4 | 0.3 | 0.0 |
| GO:0030162 | Regulation of proteolysis | 0.0 | 0.0 | 1.2 | 0.4 | 0.3 | 0.0 | 0.0 | 0.7 | 3.6 | 0.0 |
| GO:0043122 | Regulation of I-kappaB kinase NF-kappaB cascade | 0.0 | 0.0 | 0.6 | 3.3 | 0.4 | 0.0 | 0.4 | 0.0 | 1.3 | 0.0 |
| GO:0046870 | Cadmium ion binding | 0.0 | 0.0 | 0.0 | 0.5 | 1.3 | 3.1 | 0.0 | 0.8 | 0.0 | 2.3 |
| GO:0006935 | Chemotaxis | 1.8 | 0.5 | 2.0 | 0.4 | 1.5 | 0.9 | 1.5 | 0.7 | 2.9 | 1.3 |
Genes that were differentially expressed (padjusted < 0.05) by each compound were subjected to Gene Ontology enrichment analysis using the GOMiner tool with 1,000 permutations. The -log10|P| for selected GO terms are shown here. For example, genes annotated as being involved in RNA binding are enriched amongst those differentially expressed by compound Q with p < 10-7.2 and amongst those differentially expressed by compound H with p < 10-1.2.