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. 2008 Sep;24(9):1175–1183. doi: 10.1089/aid.2008.0062

Table 1.

HIV Peptide-Induced Release of IFN-γ and Trail in PBMCs of HIV-Infected Individualsa

 
% of peptides to which a positive response was detecteda
  A B C D E F G Mean ± SD
IFN-γ 7 10.7 4.7 7.4 0 0 8.3 5.4 ± 3.8
TRAIL 74.4 67.9 76.3 78.6 33.3 58.3 50 62.7 ± 15.3
IFN-γ/TRAIL 18.6 21.4 19 14.3 66.7 41.7 41.7 31.9 ± 17.6
a

PBMCs of seven HIV+CD4low subjects (A–G) were tested in ELISPOT assays for HIV-peptide-induced production of IFN-γ or TRAIL; 78 HIV peptides were tested individually in duplicate wells. In each individual the number of peptides inducing a positive response (out of the 78 peptides tested) was set as 100%. We then calculated the percentage of peptides that induced IFN-γ alone (in the absence of TRAIL), TRAIL alone (in the absence of IFN-γ), or the combination of both. Mean and SD for all subjects have been calculated and are shown in the last column.