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. 2010 May 12;16(9):2699–2708. doi: 10.1089/ten.tea.2010.0042

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Copyright 2010, Mary Ann Liebert, Inc.

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FIG. 6. — Expression profiles of (A) PRG4, (B) TGF-beta induced 68 kDa protein (TGFBI), (C) chondromodulin, (D) Dickkopf-1, (E) Fas, and (F) CASP4 show different temporal patterns for chondrogenically induced MSC-seeded constructs compared to chondrocyte-seeded constructs cultured identically for 56 days. (G) Immunohistochemical detection of PRG4 and TGFBI for day 56 cell-seeded constructs shows robust staining in chondrocyte-seeded constructs and weak staining in MSC-seeded constructs. Scale bar: 100 μm. Color images available online at www.liebertonline.com/ten.