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. Author manuscript; available in PMC: 2010 Aug 25.
Published in final edited form as: Wound Repair Regen. 2009 Jan–Feb;17(1):34–41. doi: 10.1111/j.1524-475X.2008.00439.x

Figure 2.

Figure 2

Cell motility in response to soluble wound factors. Primary keratinocytes were isolated from wild-type (WT) and CXCR3−/− mice and analyzed for response to a wound growth factor (EGF for the EGF receptor network) and the CXCR3 ligands (IP-9 and IP-10). In a two-dimensional in vitro “wound healing” assay, keratinocytes from both mice were equally responsive to EGF, but only the WT keratinocytes responded to IP-9 and IP-10 for induction of migration (mean ± SD; n=3; *p < 0.05). CXCR3, cysteine-X amino acid-cysteine receptor 3; EGF, epidermal growth factor.