Table 3.

Oklahoma Center SHFS gene-centric statistical analysis with 2248 heterozygous SNPs on chromosome 9p21

Gene	Best SNP	SNP P-value	Number of SNPs	Effective number of SNPs	Gene-centric test	HWEa
KIAA1797	rs7875153	0.00008	69	25	0.002	0.47
—	rs4446809	0.00014	—	—	0.003	0.46
—	rs10964759	0.00045	—	—	0.010	0.61
IFNE1	rs1125488	0.02503	3	1	0.025	0.10
LOC729983	rs7853123	0.00369	11	8	0.029	0.08
LOC402359	rs7848524	0.00098	8	5	0.049	0.02
LOC392298	rs3913107	0.00545	17	12	0.065	0.15
LOC646505	rs4977348	0.00535	15	12	0.066	0.49
IFNA16	rs12337907	0.02288	3	3	0.068	0.03
PLAA	rs12003612	0.02711	12	4	0.108	0.49
SLC24A2	rs10757082	0.00295	63	38	0.112	0.12
LOC402360	rs1036107	0.00657	30	20	0.131	0.20
MTAP	rs10117507	0.01581	28	9	0.142	0.03
ELAVL2	rs4977886	0.00785	50	30	0.236	0.53
LOC392288	rs11792752	0.01486	22	17	0.253	0.99
C9orf82	rs10511793	0.04801	18	6	0.288	0.30
C9orf11	rs911602	0.04525	14	8	0.362	0.89
MOBKL2B	rs4879507	0.01262	68	41	0.517	0.48
TEK	rs7035592	0.01786	71	42	0.750	0.56
MLLT3	rs7868612	0.02751	50	29	0.798	0.35
IFNA1	rs7864960	0.03402	1	—	—	0.93
IFNA6	rs660675	0.02922	1	—	—	0.83
LOC729932	rs7853123	0.00369	1	—	—	0.08

Significant SNPs in bold.

^aHWE, Hardy–Weinberg equilibrium P-value for the best SNP.