Figure 5.

Effects of DCS (30 mg/kg) and vehicle (Veh) administered after extinction training (Experiment 3) on subsequent reacquisition of cocaine self-administration in rats. Values are the mean±SEM percent of baseline lever responses for DCS or Veh administered immediately after extinction training in conjunction with brief handling (top panel); immediately after extinction training without brief handling (middle panel); and 6 h after extinction training in conjunction with brief handling (bottom panel). Significantly less than the corresponding Veh control pretreatment (^*p⩽0.05 and ^**p⩽0.01).