Table 2.
The expression of pGSK-3βTyr216 in relation to that of cell cycle-regulatory proteins
| Active GSK-3β Positive (%) |
Active GSK-3β Negative (%) |
P value | |
|---|---|---|---|
| p16 | |||
| Positive | 99 (54) | 84 (46) | < 0.001* |
| Negative | 24 (28) | 63 (72) | |
| p21 | |||
| Positive | 38 (26) | 39 (74) | < 0.001* |
| Negative | 23 (12) | 162 (88) | |
| p27 | |||
| Positive | 23 (59) | 38 (41) | 0.001* |
| Negative | 30 (3) | 149 (97) | |
| p53 | |||
| Positive | 56 (55) | 45 (45) | 0.013* |
| Negative | 69 (40) | 104 (60) | |
| pRb | |||
| Positive | 118 (45) | 142 (55) | 0.208 |
| Negative | 6 (67) | 3 (33) | |
| Cyclin D1 | |||
| Positive | 28 (53) | 25 (47) | 0.202 |
| Negative | 90 (43) | 119 (57) |
pRb: phospho-retinoblastoma protein.
* Considered to be statistically significant (< 0.05).