Skip to main content
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1966 Sep;45(9):1400–1411. doi: 10.1172/JCI105448

Effects of prolonged ethanol intake in man: role of dietary adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver.

C S Lieber, N Spritz
PMCID: PMC292820  PMID: 4162127

Full text

PDF
1400

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AMENTA J. S. A RAPID CHEMICAL METHOD FOR QUANTIFICATION OF LIPIDS SEPARATED BY THIN-LAYER CHROMATOGRAPHY. J Lipid Res. 1964 Apr;5:270–272. [PubMed] [Google Scholar]
  2. BILLING B. H., HASLAM R. M., HEIN D. E., CONLON H. J., HAMILTON D. L., MINDRUM G. M., SCHIFF L. Serum and liver lipids in patients with and without liver disease. J Lab Clin Med. 1955 Mar;45(3):363–370. [PubMed] [Google Scholar]
  3. FARQUHAR J. W., INSULL W., Jr, ROSEN P., STOFFEL W., AHRENS E. H., Jr The analysis of fatty acid mixtures by gas-liquid chromatography; construction and operation of an ionization chamber instrument. Nutr Rev. 1959 Aug;17(8 Suppl):1–30. [PubMed] [Google Scholar]
  4. FEIGELSON E. B., PFAFF W. W., KARMEN A., STEINBERG D. The role of plasma free fatty acids in development of fatty liver. J Clin Invest. 1961 Dec;40:2171–2179. doi: 10.1172/JCI104443. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. GOLDRICK B., HIRSCH J. A TECHNIQUE FOR QUANTITATIVE RECOVERY OF LIPIDS FROM CHROMATOPLATES. J Lipid Res. 1963 Oct;4:482–483. [PubMed] [Google Scholar]
  6. HIRSCH J., FARQUHAR J. W., AHRENS E. H., Jr, PETERSON M. L., STOFFEL W. Studies of adipose tissue in man. A microtechnic for sampling and analysis. Am J Clin Nutr. 1960 Jul-Aug;8:499–511. doi: 10.1093/ajcn/8.4.499. [DOI] [PubMed] [Google Scholar]
  7. HORNING E. C., AHRENS E. H., Jr, LIPSKY S. R., MATTSON F. H., MEAD J. F., TURNER D. A., GOLDWATER W. H. QUANTITATIVE ANALYSIS OF FATTY ACIDS BY GAS-LIQUID CHROMATOGRAPHY. J Lipid Res. 1964 Jan;5:20–27. [PubMed] [Google Scholar]
  8. HORNING M. G., WILLIAMS E. A., MALING H. M., BRODIE B. B. Depot fat as source of increased liver triglycerides after ethanol. Biochem Biophys Res Commun. 1960 Dec;3:635–640. doi: 10.1016/0006-291x(60)90077-2. [DOI] [PubMed] [Google Scholar]
  9. LIEBER C. S., DAVIDSON C. S. Some metabolic effects of ethyl alcohol. Am J Med. 1962 Sep;33:319–327. doi: 10.1016/0002-9343(62)90229-2. [DOI] [PubMed] [Google Scholar]
  10. LIEBER C. S., JONES D. P., DECARLI L. M. EFFECTS OF PROLONGED ETHANOL INTAKE: PRODUCTION OF FATTY LIVER DESPITE ADEQUATE DIETS. J Clin Invest. 1965 Jun;44:1009–1021. doi: 10.1172/JCI105200. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. LIEBER C. S., JONES D. P., LOSOWSKY M. S., DAVIDSON C. S. Interrelation of uric acid and ethanol metabolism in man. J Clin Invest. 1962 Oct;41:1863–1870. doi: 10.1172/JCI104643. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. LIEBER C. S., SCHMID R. The effect of ethanol on fatty acid metabolism; stimulation of hepatic fatty acid synthesis in vitro. J Clin Invest. 1961 Feb;40:394–399. doi: 10.1172/JCI104266. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Lieber C. S., Spritz N., DeCarli L. M. Role of dietary, adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver. J Clin Invest. 1966 Jan;45(1):51–62. doi: 10.1172/JCI105323. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Poggi M., Di Luzio N. R. The role of liver and adipose tissue in the pathogenesis of the ethanol-induced fatty liver. J Lipid Res. 1964 Jul;5(3):437–441. [PubMed] [Google Scholar]
  15. SCHEIG R., ISSELBACHER K. J. PATHOGENESIS OF ETHANOL-INDUCED FATTY LIVER. 3. IN VIVO AND VITRO EFFECTS OF ETHANOL ON HEPATIC FATTY ACID METABOLISM IN RATS. J Lipid Res. 1965 Apr;6:269–277. [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES