Figure 2.

Development of parasitemia in ICR (A) or C57Bl/6 (B) mice infected with PbA and treated with 2 × 2.5 or 2 × 5 mg/kg/d artemisone on days 3-6 post-inoculation. D notes mouse death; multiple deaths on a given day are noted in parentheses. Each line represents a single mouse; arrows denote treatment. ECM death in both control groups occurred on days 8-10 post-inoculation. Administration of 2 × 2.5 mg/kg/d artemisone was not curative in ICR mice, but led to complete cure in 50% of C57Bl/6 mice; treatment with 2 × 5 mg/kg/day led to complete cure in both mouse strains.