Figure 3. TREK-1 K2P channel expression in myometrium.

(A) PCR studies were carried out on both non-pregnant and pregnant tissues and cells from term pregnancy myometrium and TREK-1 transcript confirmed by sequence analysis in each case. Individual lanes represent different patient samples and are shown to illustrate representative variation. (B) 18S ribosomal RNA was used to adjust TREK gene expression relative to control gene expression. (C) Expression of TREK in term and term laboring samples was determined by Q-PRC relative to the 18S ribosomal gene as an expression control (p<.001). Data are mean ± SEM; **  = p<0.01; ***  =  p<0.001 by unpaired T-test.