Table 2.
Lung function and risk of incident type 2 diabetes during 20 years of follow-up
| FVC (l) |
P-value trend | ||||
|---|---|---|---|---|---|
| 1 (<3.97) | 2 (3.97–) | 3 (4.43–) | 4 (4.87–) | ||
| n | 1,095 | 1,106 | 1,116 | 1,117 | |
| Rate/1,000 P-years | 4.7 | 3.2 | 3.2 | 2.1 | |
| Model 1 | 2.54 (1.74–3.70) | 1.58 (1.07–2.34) | 1.56 (1.06–2.31) | 1.00 | <0.0001 |
| Model 2 | 1.94 (1.32–2.86) | 1.32 (0.89–1.97) | 1.34 (0.90–1.97) | 1.00 | 0.001 |
| Model 3 | 1.59 (1.07–2.56) | 1.14 (0.76–1.71) | 1.27 (0.85–1.88) | 1.00 | 0.03 |
| Model 4 | 1.46 (0.97–2.20) | 1.21 (0.81–1.81) | 1.03 (0.68–1.55) | 1.00 | 0.14 |
| FEV1 (l) |
P-value trend | ||||
|---|---|---|---|---|---|
| 1 (<2.95) | 2 (2.95–) | 3 (3.41–) | 4 (3.81–) | ||
| n | 1,108 | 1,107 | 1,111 | 1,108 | |
| Rate/1,000 P-years | 3.9 | 3.4 | 3.5 | 2.2 | |
| Model 1 | 2.05 (1.40–3.01) | 1.51 (1.03–2.23) | 1.56 (1.07–2.26) | 1.00 | 0.005 |
| Model 2 | 1.92 (1.29–2.86) | 1.35 (0.91–1.99) | 1.52 (1.04–2.21) | 1.00 | 0.02 |
| Model 3 | 1.74 (1.16–2.61) | 1.36 (0.92–2.03) | 1.35 (0.92–1.98) | 1.00 | 0.04 |
| Model 4 | 1.67 (1.09–2.56) | 1.31 (0.87–1.97) | 1.40 (0.94–2.08) | 1.00 | 0.11 |
| FEV1-to-FVC ratio |
P-value trend | ||||
|---|---|---|---|---|---|
| 1 (<0.71) | 2 (0.71–) | 3 (0.77–) | 4 (0.82–) | ||
| Rate/1,000 P-years | 2.5 | 3.7 | 3.2 | 3.6 | |
| Age-adjusted | 0.67 (0.46–0.96) | 0.87 (0.63–1.21) | 0.77 (0.55–1.07) | 1.00 | 0.12 |
Model 1, age-adjusted; Model 2, Model 1 + adjusted for age, BMI, smoking, physical activity, alcohol intake, social class, evidence of CHD (undiagnosed); Model 3, Model 2 + triglycerides, sBP, HDL cholesterol, blood glucose, and GGT; and Model 4, Model 3 + CRP + IL-6. P-years, person-years.