Table 1.
Unadjusted and adjusted mean CD36 mRNA/protein and Pearson product moment correlations (r)
| CD36 mRNA (log r.u.) | CD36 protein (log r.u.) | |||
|---|---|---|---|---|
| Type 2 diabetes | Nondiabetic control subjects | Type 2 diabetes | Nondiabetic control subjects | |
| n | 33 | 27 | 33 | 27 |
| Unadjusted mean | 0.23 ± 0.02† | 0.16 ± 0.02 | 0.28 ± 0.02§ | 0.18 ± 0.02 |
| Model 1 | 0.21 ± 0.02 | 0.17 ± 0.02 | 0.27 ± 0.01* | 0.21 ± 0.02 |
| Model 2 | 0.20 ± 0.02 | 0.18 ± 0.02 | 0.26 ± 0.01† | 0.20 ± 0.01 |
| CD36 mRNA (log r.u.) | NA | NA | r = 0.64‡ | r = 0.63‡ |
| PPAR-γ mRNA (log r.u.) | r = 0.73‡ | r = 0.72‡ | r = 0.33# | r = 0.46* |
| hsCRP (log mg/dl) | r = 0.55† | r = 0.21 | r = 0.45† | r = 0.43* |
| hsIL-6 (log pg/ml) | r = 0.40* | r = 0.49† | r = 0.64‡ | r = 0.49† |
| TNF-α (log pg/ml) | r = −0.20 | r = 0.09 | r = −0.28 | r = −0.02 |
| Adiponectin (log μg/ml) | r = −0.61‡ | r = −0.67‡ | r = −0.60‡ | r = −0.56† |
| BMI (kg/m2) | r = 0.20 | r = 0.03 | r = 0.09 | r = 0.17 |
| HOMA-IR (log r.u.) | r = 0.18 | r = 0.03 | r = 0.12 | r = −0.07 |
| QUICKI (log r.u.) | r = −0.20 | r = 0.05 | r = −0.16 | r = 0.19 |
Data are least squares means ± SEM unless otherwise indicated. The P value is from a t test of equality of the means. Model 1 adjusts for hypertension (HTN), hsIL-6, PPAR, adiponectin, and QUICKI. Model 2 adjusts for hsIL-6, adiponectin, and QUICKI.
*P < 0.05,
†P < 0.01,
‡P < 0.001,
§P < 0.0001,
#P = 0.08. HOMA-IR, homeostasis model assessment–insulin resistance; QUICKI, quantitative insulin sensitivity check index; r.u., relative units.