Skip to main content
NCBI home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1966 Oct;45(10):1555–1568. doi: 10.1172/JCI105462

The circulation in patients with chronic bronchitis and emphysema at rest and during exercise, with special reference to the influence of changes in blood viscosity and blood volume on the pulmonary circulation.

N Segel, J M Bishop
PMCID: PMC292837  PMID: 5925514

Full text

PDF
1555

Images in this article

1562Image
on p.1562
1562Image
on p.1562

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ASTRUP P. A simple electrometric technique for the determination of carbon dioxide tension in blood and plasma, total content of carbon dioxide in plasma, and bicarbonate content in separated plasma at a fixed carbon dioxide tension (40 mm Hg). Scand J Clin Lab Invest. 1956;8(1):33–43. doi: 10.3109/00365515609049241. [DOI] [PubMed] [Google Scholar]
  2. BETHELL F. H., LINMAN J. W. The plasma erythropoietic-stimulating factor in man; observations on patients with polycythemia vera and secondary polycythemia. J Lab Clin Med. 1957 Jan;49(1):113–127. [PubMed] [Google Scholar]
  3. BRANDFONBRENER M., LANDOWNE M., SHOCK N. W. Changes in cardiac output with age. Circulation. 1955 Oct;12(4):557–566. doi: 10.1161/01.cir.12.4.557. [DOI] [PubMed] [Google Scholar]
  4. BRAUNWALD E., KELLY E. R. The effects of exercise on central blood volume in man. J Clin Invest. 1960 Feb;39:413–419. doi: 10.1172/JCI104052. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bishop J. M., Pincock A. C., Hollyhock A., Raine J., Cole R. B. Factors affecting the measurement of the partial pressure of oxygen in blood using a covered electrode system. Respir Physiol. 1966;1(2):225–237. doi: 10.1016/0034-5687(66)90019-3. [DOI] [PubMed] [Google Scholar]
  6. CHAMBERLAIN D. A., MILLARD F. J. THE TREATMENT OF PLYCYTHAEMIA A/CHAMBERLAIN DA, MILLARD FJ: THE TREATMENT OF POLYCYTHAEMIA SECONDARY TO HYPOXIC LUNG DISEASE BY CONTINUOUS OXYGEN ADMINISTRATION. Q J Med. 1963 Oct;32:341–350. [PubMed] [Google Scholar]
  7. COURNAND A. Some aspects of the pulmonary circulation in normal man and in chronic cardiopulmonary diseases. Circulation. 1950 Nov;2(5):641–657. doi: 10.1161/01.cir.2.5.641. [DOI] [PubMed] [Google Scholar]
  8. DE FREITAS F. M., FARACO E. Z., DE AZEVEDO D. F., ZADUCHLIVER J., LEWIN I. BEHAVIOR OF NORMAL PULMONARY CIRCULATION DURING CHANGES OF TOTAL BLOOD VOLUME IN MAN. J Clin Invest. 1965 Mar;44:366–378. doi: 10.1172/JCI105150. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. DEXTER L., WHITTENBERGER J. L., HAYNES F. W., GOODALE W. T., GORLIN R., SAWYER C. G. Effect of exercise on circulatory dynamics of normal individuals. J Appl Physiol. 1951 Feb;3(8):439–453. doi: 10.1152/jappl.1951.3.8.439. [DOI] [PubMed] [Google Scholar]
  10. DONALD K. W., BISHOP J. M., CUMMING G., WADE O. L. The effect of exercise on the cardiac output and circulatory dynamics of normal subjects. Clin Sci. 1955 Feb;14(1):37–73. [PubMed] [Google Scholar]
  11. DOYLE J. T., WILSON J. S., LEPINE C., WARREN J. V. An evaluation of the measurement of the cardiac output and of the so-called pulmonary blood volume by the dye-dilution method. J Lab Clin Med. 1953 Jan;41(1):29–39. [PubMed] [Google Scholar]
  12. EBAUGH F. G., Jr, FREIS E. D., HERSHENSON L. M., KOVACH R. D., LILIENFIELD L. S., MARKS P. A., RODNAN G. P. The hematocrit of the lesser circulation in man. J Clin Invest. 1956 Dec;35(12):1385–1392. doi: 10.1172/JCI103395. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. ENSON Y., GIUNTINI C., LEWIS M. L., MORRIS T. Q., FERRER M. I., HARVEY R. M. THE INFLUENCE OF HYDROGEN ION CONCENTRATION AND HYPOXIA ON THE PULMONARY CIRCULATION. J Clin Invest. 1964 Jun;43:1146–1162. doi: 10.1172/JCI104999. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. FISHMAN A. P., RICHARDS D. W. The management of cor pulmonale in chronic pulmonary disease, with particular reference to the associated disturbances in the pulmonary circulation. Am Heart J. 1956 Jul;52(1):149–160. doi: 10.1016/0002-8703(56)90124-7. [DOI] [PubMed] [Google Scholar]
  15. GOODWIN J. F., ABDIN Z. H. The cardiogram of congenital and acquired right ventricular hypertrophy. Br Heart J. 1959 Oct;21:523–544. doi: 10.1136/hrt.21.4.523. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. GRANATH A., JONSSON B., STRANDELL T. CIRCULATION IN HEALTHY OLD MEN, STUDIED BY RIGHT HEART CATHETERIZATION AT REST AND DURING EXERCISE IN SUPINE AND SITTING POSITION. Acta Med Scand. 1964 Oct;176:425–446. doi: 10.1111/j.0954-6820.1964.tb00949.x. [DOI] [PubMed] [Google Scholar]
  17. HART D., METZ J. The estimation of red cell volume with 51Cr-labelled erythrocytes and plasma volume with radioiodinated human serum albumin. J Clin Pathol. 1962 Sep;15:459–461. doi: 10.1136/jcp.15.5.459. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. KITCHIN A. H., LOWTHER C. P., MATTHEWS M. B. The effects of exercise and of breathing oxygen-enriched air on the pulmonary circulation in emphysema. Clin Sci. 1961 Aug;21:93–106. [PubMed] [Google Scholar]
  19. KOPELMAN H., LEE G. DE J. The intrathoracic blood volume in mitral stenosis and left ventricular failure. Clin Sci. 1951 Aug;10(3):383–403. [PubMed] [Google Scholar]
  20. MOLLISON P. L., VEALL N. The use of the isotope 51Cr as a label for red cells. Br J Haematol. 1955 Jan;1(1):62–74. doi: 10.1111/j.1365-2141.1955.tb05489.x. [DOI] [PubMed] [Google Scholar]
  21. MOTLEY H. L. The mechanisms of chronic pulmonary heart disease (cor pulmonale), with and without arterial hypoxemia. Prog Cardiovasc Dis. 1959 Feb;1(3):326–340. doi: 10.1016/s0033-0620(59)80030-x. [DOI] [PubMed] [Google Scholar]
  22. OAKLEY C., GLICK G., LURIA M. N., SCHREINER B. F., Jr, YU P. N. Some regulatory mechanisms of the human pulmonary vascular bed. Circulation. 1962 Nov;26:917–930. doi: 10.1161/01.cir.26.5.917. [DOI] [PubMed] [Google Scholar]
  23. PIROFSKY B. The determination of blood viscosity in man by a method based on Poiseuille's law. J Clin Invest. 1953 Apr;32(4):292–298. doi: 10.1172/JCI102738. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. RAINE J. M., BISHOP J. M. A-a difference in O2 tension and physiological dead space in normal man. J Appl Physiol. 1963 Mar;18:284–288. doi: 10.1152/jappl.1963.18.2.284. [DOI] [PubMed] [Google Scholar]
  25. RATTO O., BRISCOE W. A., MORTON J. W., COMROE J. H., Jr Anoxemia secondary to polycythemia and polycythemia secondary to anoxemia. Am J Med. 1955 Dec;19(6):958–965. doi: 10.1016/0002-9343(55)90162-5. [DOI] [PubMed] [Google Scholar]
  26. SEGEL N., HUDSON W. A., HARRIS P., BISHOP J. M. THE CIRCULATORY EFFECTS OF ELECTRICALLY INDUCED CHANGES IN VENTRICULAR RATE AT REST AND DURING EXERCISE IN COMPLETE HEART BLOCK. J Clin Invest. 1964 Aug;43:1541–1550. doi: 10.1172/JCI105031. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. STERLING K., GRAY S. J. Determination of the circulating red cell volume in man by radioactive chromium. J Clin Invest. 1950 Dec;29(12):1614–1619. doi: 10.1172/JCI102404. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Shaw D. B., Grover R. F., Reeves J. T., Blount G., Jr Pulmonary circulation in chronic bronchitis and emphysema. Br Heart J. 1965 Sep;27(5):674–683. doi: 10.1136/hrt.27.5.674. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. VANIER T., DULFANO J., WU C., DESFORGES J. F. Emphysema, hypoxia and the polycthemic response. N Engl J Med. 1963 Jul 25;269:169–178. doi: 10.1056/NEJM196307252690401. [DOI] [PubMed] [Google Scholar]
  30. WADE O. L., BISHOP J. M., CUMMING G., DONALD K. W. A method for the rapid estimation of the percentage oxygen saturation and oxygen content of blood. Br Med J. 1953 Oct 24;2(4842):902–907. doi: 10.1136/bmj.2.4842.902. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. WENNESLAND R., BROWN E., HOPPER J., Jr, HODGES J. L., Jr, GUTTENTAG O. E., SCOTT K. G., TUCKER I. N., BRADLEY B. Red cell, plasma and blood volume in healthy men measured by radiochromium (Cr51) cell tagging and hematocrit: influence of age, somatotype and habits of physical activity on the variance after regression of volumes to height and weight combined. J Clin Invest. 1959 Jul;38(7):1065–1077. doi: 10.1172/JCI103883. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. WILLIAMS M. H., Jr, ZOHMAN L. R. Cardiopulmonary function in chronic obstructive emphysema. Am Rev Respir Dis. 1959 Nov;80:689–699. doi: 10.1164/arrd.1959.80.5.689. [DOI] [PubMed] [Google Scholar]
  33. WITHAM A. C., FLEMING J. W., BLOOM W. L. The effect of the intravenous administration of dextran on cardiac output and other circulatory dynamics. J Clin Invest. 1951 Sep;30(9):897–902. doi: 10.1172/JCI102509. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. YIENGST M. J., SHOCK N. W. Blood and plasma volume in adult males. J Appl Physiol. 1962 Mar;17:195–198. doi: 10.1152/jappl.1962.17.2.195. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES