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The effect of LPS on systemic cytokine levels. Animals received LPS, HSA and IaIp as described in Methods. Cytokines were measured by radioimmunoassay 3, 6, 12, 24, 48 and 72 hours later. Results were compared by Two-way ANOVA. A) TNF-alpha, p=0.0313; B) IL-10, p=0.0377; C) IL-12p70, p=0.0024; D) IL-6, p=0.649; E) IFN-gamma, p=0.141; F) MCP-1, p=0.4948.
